May 10: World Lupus Day

Lupus, also known as Systemic Lupus Erythematosus (SLE) is a chronic autoimmune condition where the immune system mistakenly attacks the body’s healthy tissues and organs, leading to widespread inflammation. It can impact several areas of the body, including:

• Skin: Common symptoms include rashes, especially the well-known “butterfly rash” across the cheeks.
• Joints: Pain and swelling can resemble arthritis.
• Kidneys: Lupus nephritis, a severe inflammation of the kidneys, can result in long-term complications.
• Heart and Lungs: Inflammation can cause conditions like pericarditis (around the heart) or pleuritis (around the lungs).
• Blood and Brain: Lupus may lead to anemia, clotting disorders, or neurological symptoms such as headaches, confusion, and memory challenges.

Other Symptoms of Lupus

While lupus symptoms can vary widely, common features include fatigue, joint pain, and sensitivity to sunlight. The unpredictable nature of the disease—marked by periods of flares and remission—makes it challenging for those affected.

• Sensitivity to sunlight or fluorescent light, often causing rashes or lesions
• Hair thinning or loss
• Depression and anxiety
• Raynaud’s phenomenon: Fingers and toes turning white or blue in response to cold or stress
• Mouth sores

Lupus symptoms can vary widely, making early diagnosis and tailored management crucial for improving quality of life.

AiArthritis diseases share common features such as flares, where symptoms worsen for hours to months, and improvements with physical activity, while rest can make symptoms worse. Genetic predisposition or mutations can lead to these conditions running in families, and uncontrolled inflammation often results in comorbidities, affecting 70% of patients.

Key symptoms include:

• Severe fatigue that persists despite rest or stimulants
• Brain fog, making concentration difficult
• Flu-like sensations like nausea and muscle weakness
• Low-grade fevers (higher in autoinflammatory diseases)
• Joint stiffness, especially in the morning or after long periods of inactivity
• Sudden, shifting joint pain that starts and stops abruptly

An estimated 5 million people worldwide are living with lupus, and approximately 90% of those diagnosed are women. Lupus often develops between the ages of 15 and 45, though it can affect people of all ages, genders, and ethnicities. While its exact cause remains unknown, researchers believe it results from a combination of genetic predisposition, hormonal influences, and environmental triggers, such as infections or stress.

Lupus is sometimes referred to as "the great imitator" because its symptoms often resemble those of other illnesses, leading to significant delays in diagnosis. On World Lupus Day, advocates strive to:

• Raise awareness about the early signs and symptoms of lupus.
• Improve access to care by advocating for patient-centered support and healthcare resources.
• Break down stigma associated with invisible illnesses and chronic pain conditions.
• Support research efforts to find better treatments and ultimately a cure.



For those living with lupus, the day is also a chance to amplify their voices and share personal stories to help others understand the challenges they face.

World Lupus Day is not only about raising awareness but also advocating for:

• Increased funding for research to develop targeted therapies.
• Collaboration among global health organizations to tackle disparities in lupus care.
• Improved education for medical professionals to reduce diagnostic delays.



Additionally, community-focused initiatives foster hope and connection among those affected, reminding them that they are not alone.