Dieta, investigación y artritis inducida por adyuvante: una presentación especial del ACR.
Special Series: Reporting from the American College of Rheumatology (ACR) Scientific Meeting 2020
AiArthritis Voices 360 Full Episode 58
Air Date: March 7, 2021
Esta semana, únase a su paciente coanfitriona Deb Constien mientras informa desde la Conferencia del Colegio Americano de Reumatología de 2020 sobre Modificaciones Dietéticas y el Microbioma como posibles opciones terapéuticas futuras para el tratamiento de AiEnfermedades artríticas. Deb es una dietista titulada jubilada que vive con artritis reumatoide desde hace 39 años. Asistió a dos sesiones fascinantes sobre estos temas en la Conferencia ACR 2020 y ofrece una presentación sobre el estado actual de la investigación para todos aquellos que no pudimos asistir a las sesiones.
AiArthritis cree que el futuro de la reumatología reside en la medicina de precisión y la toma de decisiones compartida, donde la genética, el estilo de vida, el entorno y el historial médico del paciente influyen en la determinación del mejor tratamiento, que se decidirá conjuntamente entre el paciente y su reumatólogo. Esta visión del futuro de la atención médica dejaría de basarse en enfoques estandarizados para el tratamiento de enfermedades, donde los pacientes se someten a una serie de medicamentos ineficaces (terapia escalonada) hasta que encuentran uno que funcione bien en su caso.
Los investigadores creen estar muy cerca de identificar biomarcadores específicos que puedan determinar las necesidades dietéticas únicas de un paciente que ayudarían, en conjunto con terapias farmacológicas, a reducir los niveles de inflamación en el cuerpo. Deb nos guía a través de la nueva investigación sobre modificaciones dietéticas y el microbioma y sus respectivos roles en el manejo de los niveles de inflamación en pacientes que sufren de AiLas enfermedades artríticas, así como la forma en que podrían utilizarse en el futuro de la medicina de precisión.
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Show Notes:
Episode 58:
Diet, Research, & AiArthritis - an ACR Special Presentation
00:52 - Deb welcomes listeners.
01:09 - Deb is a patient living with RA and a recurring Voices 360 co-host, as well as a retired Registered Dietitian
01:30 - This episode is based on two 2020 American College of Rheumatology Conference session titled: Modulation of RA Activity through Dietary Restoration of the Microbiome and Trials of Diet on Rheumatoid Arthritis
02:10 - The microbiome is a new frontier in precision medicine for the treatment of AiArthritis Diseases.
03:59 - Dietary interventions have not yet been established as a complementary treatment for RA like it has been for inflammatory bowel disease, but researchers believe they are close to finding a connection.
04:24 - The microbiome is a promising new way to monitor health and use it as a high dimensional biomarker to improve patient outcomes.
05:35 - Bacteria in your gut can impact inflammation.
06:23 - The Inflammatory Arthritis Microbiome Consortium (IAMC) collected diagnostics from stool and blood to examine bacteria and how inflammation may be connected to each different strain of bacteria found in the intestines.
07:31 - The IAMC is also studying how genetics may impact inflammatory arthritis.
08:04 - One study looked at the impact of a diet high in anti-inflammatory foods on RA patients.e
09:31 - The anti-inflammatory diet excluded soy, gluten, and refined sugar, but included some dairy to make it more palatable to the patients.
11:19 - Some patients did not improve at all with the highly restrictive diet, but some had improvements in pain and fatigue.
12:51 - Deb has done a 30 day Elimination Diet to try and identify inflammatory triggers, but none of the common triggers impacted her pain at all.
13:16 - Deb believes that a newly diagnosed patient might have better results than someone like her who has had RA for decades.
15:11 - Pain, fatigue, and general sense of wellness improved for the patients that had measurable results from the diet changes.
15:58 - There was discussion in the session of possibly pre-treating patients with antibiotics or cleanses to prepare patients for starting an anti-inflammatory diet as a potential next step in the research.
19:13 - To discuss this topic in more depth, visit us @IFAiArthritis on all social media platforms, email us at podcast@aiarthritis.org, or sign up to join us inside our new project community AiArthritis Voices @ aiarthritis.org/aiarthritisvoices
20:26 - Follow us anywhere you listen to podcasts and give us a 5-Star Rating
20:38 - To support the show, consider making a donation on our website at aiarthritis.org
Sus coanfitriones e invitados: ¿Quiénes están en la mesa en este episodio?
Tiffany Westrich-Robertson
Tiffany is the CEO at International Foundation for AiArthritis and uses her professional expertise in mind-mapping and problem solving to help others, like her, who live with AiArthritis diseases work in unison to identify and solve unresolved community issues. For the last several years, she has continued her education in research, including becoming a professional focus group moderator, and translated this experience at our organization to develop award-winning, innovative projects that are taking patient engagement to next levels.
Tiffany has served on several advisory boards, including those to advance patient voices in policy, clinical trials, and precision medicine. In addition to reviewing grants at PCORI and for the Department of Defense, she was the sole patient grant reviewer for the National Institute of Arthritis and Musculoskeletal and Skin diseases from 2015-2018. She currently participates as a Patient Research Partner for OMERACT (Outcome Measures in Rheumatology), co-leads our organizations' international effort to advance patient voices in rheumatology research (the ACTion Council) and has dedicated her professional career to developing other patients to utilize their voices to impact the future of millions.
Patrice Johnson
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